Cannabidiol (CBD), and other phytochemical constituents of cannabis are considered to be generally safe. In hemp’s thousands of years of use there has not been one recorded fatality or major illness contributed to it’s use that we know of. In high servings some people can experience a slight sedative effect. In very high servings (upwards of 200mg of CBD per serving) some people experience what’s being labeled as Dysphoria, an unpleasant emotional state. This is incredibly rare though, and has only been mentioned when using abnormally high amounts of CBD.